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Signs and Symptoms of Sezary Syndrome

Sezary syndrome is a type of non-Hodgkin’s lymphoma belonging to the family of cutaneous t-cell lymphomas. The most common t-cell lymphoma is mycosis fungoides, and Sezary syndrome is sometimes considered to be late-stage mycosis fungoides, with lymph involvement.

Mycosis fungoides is far more common than Sezary syndrome. In the western world, there is only one case of Sezary syndrome for every 300,000 people. We have put together a list of common signs and symptoms of Sezary syndrome below.

The Signs and Symptoms of Sezary Syndrome are as follows:

  • A scaly red rash in areas of the body that are not exposed to the sun
  • Excema-like patches on the skin
  • Thickened, red areas on the skin
  • Lesions on the skin that do not heal with normal medication
  • Skin all over the body that is reddened, itchy and painful

Sezary syndrome is sometimes called red man syndrome because the skin of the entire body sometimes turns bright red. Sezary syndrome is twice as common in males than females. The median age of diagnosis is between fifty-five and sixty years of age. The median survival rate for Sezary syndrome is two to four years.

There are currently no known causes of Sezary syndrome.

Diagnosis of Sezary Syndrome

A diagnosis of Sezary syndrome is first made through a skin examination. Patients with Sezary syndrome have symptoms such as rashes or lesions that do not respond to normal medication. A blood test reveals changes in the  levels of lymphocytes in the blood that are indicative of cutaneous t-cell lymphoma.

Books For People With Signs and Symptoms of Sezary Syndrome

21st Century Ultimate Medical Guide to Mycosis Fungoides and Sezary Syndrome – Authoritative, Practical Clinical Information for Physicians and Patients, Treatment Options (Two CD-ROM Set)
PM Medical Health News
The Official Patient’s Sourcebook on Mycosis Fungoides and the Sezary Syndrome: A Revised and Updated Directory for the Internet Age
Icon Health Publications

What You Always Wanted To Know About Mycosis Fungoides And Sézary Syndrome (Medical Basic Guides)
Various Authors
Cutaneous T-Cell Lymphoma: Mycosis Fungoides and Sezary Syndrome (Dermatology: Clinical & Basic Science)
Herschel S. Zackheim

Sezary Syndrome Resources

General Patient Resources

  • The Doctor’s Doctor

Expert-reviewed information summary about the treatment of mycosis fungoides and the Sézary syndrome.

  • Genetic and Rare Diseases Information Center (GARD)

A US Department of Health and Human Service project providing information on genetic and rare diseases. A comprehensive body of resources on Sezary syndrome.

  • RD

Sezary syndrome information including symptoms, diagnosis, misdiagnosis, treatment, causes, patient stories, videos, forums, prevention, and prognosis.

  • DermNet NZ

Facts about Sezary Syndrome from DermNet NZ.

  • Skin Disorders . net

Information on Sezary’s Syndrome with there causes, symptoms, diagnosis and treatment.

  • Lymphoma Info . net

Information and resources on Cutaneous T-Cell Non-Hodgkin’s Lymphoma / Mycosis Fungoides / Sezary Syndrome, a cancer of the lymphatic system.

  • Experience Project

Do You Have Sezary Syndrome? Join friendly people sharing true stories in the I Have Sezary Syndrome group. Find support forums, advice and chat with groups who share this cancer.

Medical Resources

  • Pub Med

A service of the US National Library of Medicine.