Mixed Connective Tissue Disease (MCTD) Signs and Symptoms
Mixed Connective Tissue Disease (MCTD) is a diagnosis given to a collection of symptoms that have similarities to lupus, scleroderma, rheumatoid arthritis, and other connective tissue diseases. It is a chronic autoimmune condition whose signs and symptoms overlap with signs and symptoms of the afore-mentioned diseases. We have put together a list of common signs and symptoms of mixed connective tissue disease (MCTD) below.
Also, we have information on diagnosis, helpful books and valuable resources for patients.
The Most Common Signs and Symptoms of Mixed Connective Tissue Disease include:
- Symptoms of Raynaud’s phenomena – cold sensitivity of the fingers and toes, with tingling, numbness and color changes of the skin
- Rashes, including a Lupus-like rash on the face
- Swollen hands
- Swollen fingers
- Joint pain
- Muscle weakness
- Shortness of breath
- Fever
- Abdominal pain
- Dry eyes
- Dry mouth
- Difficulty swallowing
- Hair loss
- Spider veins on the face and hands
- Swollen lymph nodes
- Shoulder pain
- Hip pain
- Heartburn
Diagnosis of Mixed Connective Tissue Disease
A diagnosis of mixed connective tissue disease is given when lupus, scleroderma and rheumatoid arthritis symptoms overlap. A diagnosis of mixed connective tissue disease may be difficult, and the disease sometimes progresses to a later diagnosis of one of these conditions. Eight out of ten patients with mixed connective tissue disease are women. It can occur at any age, though the average age of onset is late adolescence to the thirties. Sometimes the symptoms are fairly mild, and can disappear for long periods of time.
Books for People With Signs and Symptoms of Mixed Connective Tissue Disease
| Mixed Connective Tissue Disease – A Medical Dictionary, Bibliography, and Annotated Research Guide to Internet References ICON Health Publications |
Connective Tissue Diseases: Holistic Therapy Options–Sjoegren¿s Syndrome; Systemic Sclerosis – Scleroderma; Systemic Lupus Erythematosus; Discoid Lupus Erythematosus; Secondary and Primary Raynaud¿s phenomenon; Raynaud¿s Disease; Polymyositis ¿ Dermatomyositis Hannelore Helbing-Sheafe |
| Mixed Connective Tissue Disease and Antinuclear Antibodies: International Symposium Proceedings (International Congress) Reiji Kasukawa |
Living Well with Autoimmune Disease: What Your Doctor Doesn’t Tell You…That You Need to Know Mary J. Shomon |
Mixed Connective Tissue Disease (MCTD) Resources
General Patient Resources
- American Autoimmune Related Diseases Association
Information, advocacy, events and forum.
http://www.aarda.org/forum2/comments.php?DiscussionID=29
- Experience Project
Anonymously connect with people who share your experiences– like those who say ‘I Have Mixed Connective Tissue Disease’. Read hundreds of true stories, share your own story anonymously, get feedback and comments, chat in the discussion forum, help others, meet new friends, and so much more– all free.
http://www.experienceproject.com/groups/Have-Mixed-Connective-Tissue-Disease/93503
- Lupus MCTD Foundation
An inactive site for reading only.
http://www.lupusmctd.com/index.php?PHPSESSID=602a5abb1cc69b6e2014494e6c0e6887;www
Medical Resources
- Mayo Clinic
Comprehensive overview covers symptoms, treatments for this rare autoimmune disorder.
http://www.mayoclinic.com/health/mixed-connective-tissue-disease/DS00675
- MedicineNet . com
Information on mixed connective tissue disease (MCTD) symptoms, types, treatment and prognosis. MCTD is an overlap of lupus, scleroderma and polymyositis.
http://www.medicinenet.com/mixed_connective_tissue_disease/article.htm
- Medscape Reference
http://emedicine.medscape.com/article/335815-overview
- Professional articles, clinical insights and the latest treatments and technologies.
http://emedicine.medscape.com/article/335815-overview

