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Signs and Symptoms of Acromegaly

Acromegaly is a rare hormone disorder in which the pituitary gland produces too much growth hormone after puberty. Acromegaly occurs only in adults. A related condition, gigantism, occurs in children. If the condition occurs before puberty, it is gigantism, and if it occurs after puberty or during middle age, it is acromegaly. Because acromegaly tends to advance slowly, symptoms may remain undetected for up to 10 years. We have listed the common signs and symptoms of acromegaly below.

The Common Signs and Symptoms of Acromegaly are as follows:

  • Enlargement of the hands, feet, nose, lips and ears
  • Wide, stubby fingers
  • Thickening of the skin
  • Oily skin
  • Broadened facial features
  • Brow protusion
  • Protusion of the lower jaw so that the lower bite extends beyond the upper bite
  • Gaps between the teeth
  • Enlargement of the tongue
  • Skin tags
  • Excessive sweating
  • Body odor
  • Enlarged vocal cords and sinuses
  • Deep, hoarse voice
  • Slow speech
  • Severe snoring due to sleep apnea
  • Back pain
  • Barrel chest
  • Enlargement of the heart
  • Menstrual cycle abnormalities
  • Breast discharge in women
  • Visual disturbances
  • Impotence in men

Acromegaly tends to develop slowly. If you notice any of the above signs and symptoms of acromeglay, see your doctor. Untreated symptoms can lead to many complications, and even premature death.

Diagnosis of Acromegaly

A diagnosis of acromeglay will likely be made after the following tests: IGF-1 tests measuring levels of a related growth hormone IGF-1; a glucose tolerance test, and an MRI of the pituitary gland to pinpoint the size and location of the tumor. If no tumor is found, then additional MRI’s of the chest and abdomen may be done to rule out acromegaly caused by other tumors of the pancreas, lungs, and adrenal glands.

Books for People with Signs and Symptoms of Acromegaly

The Official Patient’s Sourcebook on Acromegaly: A Revised and Updated Directory for the Internet Age The Pituitary Gland as a Factor in Acromegaly and Giantism
Woods Hutchinson

Acromegaly and Its Management
A. G. Harris
Maximilian Sternberg

Acromegaly Resources

General Patient Resources

Acromegaly . org

A satellite site of the Pituitary Network Association

E Medicine Health

A comprehensive acromegaly overview including symptoms, causes, treatment, and when to seek medical care.

Acromegaly Info . com

Update your understanding of the challenges of making an accurate acromegaly diagnosis and tools you can use. Plus, learn more about early intervention strategies and their vital role in patient management.

Daily Strength

Meet over 317 friendly, supportive people sharing their experiences with Acromegaly. Real help from real people.

Acromegaly Forum

This forum has been created to increase awareness of the issues surrounding the diagnosis and treatment of patients with acromegaly.

MD Junction

Discussions, Q&A and friends dealing with Acromegaly


Information including symptoms, diagnosis, misdiagnosis, treatment, causes, patient stories, videos, forums, prevention, and prognosis.

Medical Resources

Mayo Clinic

Comprehensive overview covers symptoms, causes, treatment of this hormonal disorder.

Medline Plus

A service of the US National Library of Medicine.

Pub Med Health

Reviews causes, symptoms, incidence, risk factors, treatment, prognosis and complications.